Vampire Survivors Weapons Upgrade Combinations Guide

Some items will only appear when you unlock the related achievement:

Candelabra – Get Santa water to Level 4
Spellbinder – Get Runetracer to Level 7
Empty Tome – Hold 6 different weapons at once
Fire wand – Destroy 20 light sources
Clover – Find a clover
Cross – Find a rosary

For every power up chosen the cost will go up for the next level and for every other different power up, this makes it that you have to be careful in the order of the upgrades to optimize your coins

Upgrade path on a single skill
Level 0 – base cost
Level 1 – base cost * 2.2
Level 2 – base cost * 3.6
Level 3 – base cost * 5.2
Level 4 – base cost * 7.0

For each level upgraded all other skills will increase the cost by 10% of their base cost * number of levels +1.
Example: Greed at level 2 -> 3 costs 720, if there are three other upgraded power ups then its cost to upgrade to level 3 is:
(200 * (number of levels + 1) * 0.1) * (number of levels in other power ups) + base cost * 3.6
= (200 * 3 * 0.1) * 3 + 720 = 900

This causes that to get better use out of your coins you should upgrade starting with the most expensive cost downwards since the 10% increase in cost is higher in power ups with higher base cost. Since there is no penalty to refunding you can try it for yourself